Lymphocyte Immunization Therapy (LIT)
When Lymphocyte Immunization Therapy Is Needed?
Lymphocyte Immunization Therapy is recommended when recurrent miscarriages, repeated IVF failures, and unexplained infertility persist. This therapeutic approach addresses underlying immunological factors, offering hope and solutions for couples seeking successful pregnancies.
Indications
Unexplained Repeated pregnancy loss
Unexplained recurrent implantation failure
Unexplained infertility
Unexplained late pregnancy losses
Immunological testing
Lymphocyte crossmatch: Negative
Tnf alpha raised
Endometrial CD57 cells positive
NK cells: CD3, CD4 raised. CD16+56 low
Raised antithyroid antibodies (AntiTPO and Antithyroglobulin)
Prerequisites to LIT
Blood group of both the partners (or donor) to know about Rh status
Blood group of both the partners (or donor) to know about Rh status
Infection profile of both the partners Or the patient and the donor (in case of use of donor lymphocytes) (HIV, HCV, VDRL, HBsAg)
